Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Wnt3a  wingless-type MMTV integration site family, member 3A   (Synonyms: Wnt-3a)
Results	Reference
1*	J:84706 Assimacopoulos S, Grove EA, Ragsdale CW, Identification of a Pax6-dependent epidermal growth factor family signaling source at the lateral edge of the embryonic cerebral cortex. J Neurosci. 2003 Jul 23;23(16):6399-403
1	J:142365 Barry G, Piper M, Lindwall C, Moldrich R, Mason S, Little E, Sarkar A, Tole S, Gronostajski RM, Richards LJ, Specific glial populations regulate hippocampal morphogenesis. J Neurosci. 2008 Nov 19;28(47):12328-40
1*	J:67304 Bulchand S, Grove EA, Porter FD, Tole S, LIM-homeodomain gene Lhx2 regulates the formation of the cortical hem. Mech Dev. 2001 Feb;100(2):165-75
1	J:124082 Cambray N, Wilson V, Two distinct sources for a population of maturing axial progenitors. Development. 2007 Aug;134(15):2829-40
1	J:160559 Caronia G, Wilcoxon J, Feldman P, Grove EA, Bone morphogenetic protein signaling in the developing telencephalon controls formation of the hippocampal dentate gyrus and modifies fear-related behavior. J Neurosci. 2010 May 5;30(18):6291-301
1	J:232481 Caronia-Brown G, Anderegg A, Awatramani R, Expression and functional analysis of the Wnt/beta-catenin induced mir-135a-2 locus in embryonic forebrain development. Neural Dev. 2016;11:9
1	J:110657 Cheng X, Hsu CM, Currle DS, Hu JS, Barkovich AJ, Monuki ES, Central roles of the roof plate in telencephalic development and holoprosencephaly. J Neurosci. 2006 Jul 19;26(29):7640-9
1	J:184876 Chiara F, Badaloni A, Croci L, Yeh ML, Cariboni A, Hoerder-Suabedissen A, Consalez GG, Eickholt B, Shimogori T, Parnavelas JG, Rakic S, Early B-cell factors 2 and 3 (EBF2/3) regulate early migration of Cajal-Retzius cells from the cortical hem. Dev Biol. 2012 May 1;365(1):277-89
1	J:301713 Chizhikov VV, Iskusnykh IY, Fattakhov N, Fritzsch B, Lmx1a and Lmx1b are Redundantly Required for the Development of Multiple Components of the Mammalian Auditory System. Neuroscience. 2021 Jan 1;452:247-264
1	J:281616 Chizhikov VV, Iskusnykh IY, Steshina EY, Fattakhov N, Lindgren AG, Shetty AS, Roy A, Tole S, Millen KJ, Early dorsomedial tissue interactions regulate gyrification of distal neocortex. Nat Commun. 2019 Nov 15;10(1):5192
1*	J:161290 Chizhikov VV, Lindgren AG, Mishima Y, Roberts RW, Aldinger KA, Miesegaes GR, Currle DS, Monuki ES, Millen KJ, Lmx1a regulates fates and location of cells originating from the cerebellar rhombic lip and telencephalic cortical hem. Proc Natl Acad Sci U S A. 2010 Jun 8;107(23):10725-30
1	J:154611 Chou SJ, Perez-Garcia CG, Kroll TT, O'Leary DD, Lhx2 specifies regional fate in Emx1 lineage of telencephalic progenitors generating cerebral cortex. Nat Neurosci. 2009 Nov;12(11):1381-9
1	J:254118 De Clercq S, Keruzore M, Desmaris E, Pollart C, Assimacopoulos S, Preillon J, Ascenzo S, Matson CK, Lee M, Nan X, Li M, Nakagawa Y, Hochepied T, Zarkower D, Grove EA, Bellefroid EJ, DMRT5 Together with DMRT3 Directly Controls Hippocampus Development and Neocortical Area Map Formation. Cereb Cortex. 2018 Feb 1;28(2):493-509
1*	J:18916 Dickinson ME, Krumlauf R, McMahon AP, Evidence for a mitogenic effect of Wnt-1 in the developing mammalian central nervous system. Development. 1994 Jun;120(6):1453-71
1	J:205579 Dixit R, Wilkinson G, Cancino GI, Shaker T, Adnani L, Li S, Dennis D, Kurrasch D, Chan JA, Olson EC, Kaplan DR, Zimmer C, Schuurmans C, Neurog1 and Neurog2 control two waves of neuronal differentiation in the piriform cortex. J Neurosci. 2014 Jan 8;34(2):539-53
1*	J:188692 Dixit R, Zimmer C, Waclaw RR, Mattar P, Shaker T, Kovach C, Logan C, Campbell K, Guillemot F, Schuurmans C, Ascl1 participates in Cajal-Retzius cell development in the neocortex. Cereb Cortex. 2011 Nov;21(11):2599-611
1	J:274335 Draganova K, Zemke M, Zurkirchen L, Valenta T, Cantu C, Okoniewski M, Schmid MT, Hoffmans R, Gotz M, Basler K, Sommer L, Wnt/beta-catenin signaling regulates sequential fate decisions of murine cortical precursor cells. Stem Cells. 2015 Jan;33(1):170-82
1	J:285759 Esteve P, Crespo I, Kaimakis P, Sandonis A, Bovolenta P, Sfrp1 Modulates Cell-signaling Events Underlying Telencephalic Patterning, Growth and Differentiation. Cereb Cortex. 2019 Mar 1;29(3):1059-1074
1*	J:136720 Friedrichs M, Larralde O, Skutella T, Theil T, Lamination of the cerebral cortex is disturbed in Gli3 mutant mice. Dev Biol. 2008 Jun 1;318(1):203-14
1	J:174118 Fuccillo M, Rutlin M, Fishell G, Removal of Pax6 partially rescues the loss of ventral structures in Shh null mice. Cereb Cortex. 2006 Jul;16 Suppl 1:i96-102
1	J:82309 Garel S, Huffman KJ, Rubenstein JL, Molecular regionalization of the neocortex is disrupted in Fgf8 hypomorphic mutants. Development. 2003 May;130(9):1903-14
1	J:240473 Geng X, Acosta S, Lagutin O, Gil HJ, Oliver G, Six3 dosage mediates the pathogenesis of holoprosencephaly. Development. 2016 Dec 01;143(23):4462-4473
1	J:140315 Geng X, Speirs C, Lagutin O, Inbal A, Liu W, Solnica-Krezel L, Jeong Y, Epstein DJ, Oliver G, Haploinsufficiency of Six3 fails to activate Sonic hedgehog expression in the ventral forebrain and causes holoprosencephaly. Dev Cell. 2008 Aug;15(2):236-47
1	J:270535 Godbole G, Shetty AS, Roy A, D'Souza L, Chen B, Miyoshi G, Fishell G, Tole S, Hierarchical genetic interactions between FOXG1 and LHX2 regulate the formation of the cortical hem in the developing telencephalon. Development. 2018 Jan 9;145(1):dev154583
1	J:226667 Goodnough LH, Dinuoscio GJ, Ferguson JW, Williams T, Lang RA, Atit RP, Distinct requirements for cranial ectoderm and mesenchyme-derived wnts in specification and differentiation of osteoblast and dermal progenitors. PLoS Genet. 2014 Feb;10(2):e1004152
1	J:102085 Grove EA, Tole S, Patterning events and specification signals in the developing hippocampus. Cereb Cortex. 1999 Sep;9(6):551-61
1*	J:48569 Grove EA, Tole S, Limon J, Yip L, Ragsdale CW, The hem of the embryonic cerebral cortex is defined by the expression of multiple Wnt genes and is compromised in Gli3-deficient mice. Development. 1998 Jun;125(12):2315-25
1*	J:21617 Gunther T, Struwe M, Aguzzi A, Schughart K, Open brain, a new mouse mutant with severe neural tube defects, shows altered gene expression patterns in the developing spinal cord. Development. 1994 Nov;120(11):3119-30
1	J:119019 Gutin G, Fernandes M, Palazzolo L, Paek H, Yu K, Ornitz DM, McConnell SK, Hebert JM, FGF signalling generates ventral telencephalic cells independently of SHH. Development. 2006 Aug;133(15):2937-46
1	J:196059 Hodge RD, Garcia AJ 3rd, Elsen GE, Nelson BR, Mussar KE, Reiner SL, Ramirez JM, Hevner RF, Tbr2 expression in Cajal-Retzius cells and intermediate neuronal progenitors is required for morphogenesis of the dentate gyrus. J Neurosci. 2013 Feb 27;33(9):4165-80
1	J:139170 Imayoshi I, Shimogori T, Ohtsuka T, Kageyama R, Hes genes and neurogenin regulate non-neural versus neural fate specification in the dorsal telencephalic midline. Development. 2008 Aug;135(15):2531-41
1	J:98539 Kimura J, Suda Y, Kurokawa D, Hossain ZM, Nakamura M, Takahashi M, Hara A, Aizawa S, Emx2 and Pax6 function in cooperation with Otx2 and Otx1 to develop caudal forebrain primordium that includes future archipallium. J Neurosci. 2005 May 25;25(21):5097-108
1	J:297062 Kinare V, Iyer A, Padmanabhan H, Godbole G, Khan T, Khatri Z, Maheshwari U, Muralidharan B, Tole S, An evolutionarily conserved Lhx2-Ldb1 interaction regulates the acquisition of hippocampal cell fate and regional identity. Development. 2020 Oct 19;147(20):dev187856
1	J:107400 Laurikkala J, Mikkola ML, James M, Tummers M, Mills AA, Thesleff I, p63 regulates multiple signalling pathways required for ectodermal organogenesis and differentiation. Development. 2006 Apr;133(8):1553-63
1	J:59283 Lee SM, Tole S, Grove E, McMahon AP, A local Wnt-3a signal is required for development of the mammalian hippocampus. Development. 2000 Feb;127(3):457-67
1	J:272637 Liu B, Zhou K, Wu X, Zhao C, Foxg1 deletion impairs the development of the epithalamus. Mol Brain. 2018 Feb 2;11(1):5
1	J:179217 Liu HX, Grosse AS, Iwatsuki K, Mishina Y, Gumucio DL, Mistretta CM, Separate and distinctive roles for Wnt5a in tongue, lingual tissue and taste papilla development. Dev Biol. 2012 Jan 1;361(1):39-56
1	J:338207 Moreau MX, Saillour Y, Elorriaga V, Bouloudi B, Delberghe E, Deutsch Guerrero T, Ochandorena-Saa A, Maeso-Alonso L, Marques MM, Marin MC, Spassky N, Pierani A, Causeret F, Repurposing of the multiciliation gene regulatory network in fate specification of Cajal-Retzius neurons. Dev Cell. 2023 Jun 7;
1	J:330186 Nguyen H, Sokpor G, Parichha A, Pham L, Saikhedkar N, Xie Y, Ulmke PA, Rosenbusch J, Pirouz M, Behr R, Stoykova A, Brand-Saberi B, Nguyen HP, Staiger JF, Tole S, Tuoc T, BAF (mSWI/SNF) complex regulates mediolateral cortical patterning in the developing forebrain. Front Cell Dev Biol. 2022;10:1011109
1	J:150347 Paek H, Gutin G, Hebert JM, FGF signaling is strictly required to maintain early telencephalic precursor cell survival. Development. 2009 Jul;136(14):2457-65
1	J:331057 Parichha A, Datta D, Suresh V, Chatterjee M, Holtzman MJ, Tole S, Dentate gyrus morphogenesis is regulated by beta-catenin function in hem-derived fimbrial glia. Development. 2022 Nov 1;149(21):dev200953
1	J:320719 Parichha A, Suresh V, Chatterjee M, Kshirsagar A, Ben-Reuven L, Olender T, Taketo MM, Radosevic V, Bobic-Rasonja M, Trnski S, Holtzman MJ, Jovanov-Milosevic N, Reiner O, Tole S, Constitutive activation of canonical Wnt signaling disrupts choroid plexus epithelial fate. Nat Commun. 2022 Feb 2;13(1):633
1	J:162001 Piper M, Barry G, Hawkins J, Mason S, Lindwall C, Little E, Sarkar A, Smith AG, Moldrich RX, Boyle GM, Tole S, Gronostajski RM, Bailey TL, Richards LJ, NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1. J Neurosci. 2010 Jul 7;30(27):9127-39
1*	J:11028 Roelink H, Nusse R, Expression of two members of the Wnt family during mouse development--restricted temporal and spatial patterns in the developing neural tube. Genes Dev. 1991 Mar;5(3):381-8
1	J:220958 Rosenthal EH, Tonchev AB, Stoykova A, Chowdhury K, Regulation of archicortical arealization by the transcription factor Zbtb20. Hippocampus. 2012 Nov;22(11):2144-56
1	J:336383 Ruiz-Reig N, Andres B, Huilgol D, Grove EA, Tissir F, Tole S, Theil T, Herrera E, Fairen A, Lateral Thalamic Eminence: A Novel Origin for mGluR1/Lot Cells. Cereb Cortex. 2017 May 1;27(5):2841-2856
1	J:166617 Sakurai Y, Kurokawa D, Kiyonari H, Kajikawa E, Suda Y, Aizawa S, Otx2 and Otx1 protect diencephalon and mesencephalon from caudalization into metencephalon during early brain regionalization. Dev Biol. 2010 Nov 15;347(2):392-403
1*	J:215514 Saulnier A, Keruzore M, De Clercq S, Bar I, Moers V, Magnani D, Walcher T, Filippis C, Kricha S, Parlier D, Viviani L, Matson CK, Nakagawa Y, Theil T, Gotz M, Mallamaci A, Marine JC, Zarkower D, Bellefroid EJ, The doublesex homolog Dmrt5 is required for the development of the caudomedial cerebral cortex in mammals. Cereb Cortex. 2013 Nov;23(11):2552-67
1	J:141122 Shibata M, Kurokawa D, Nakao H, Ohmura T, Aizawa S, MicroRNA-9 modulates Cajal-Retzius cell differentiation by suppressing Foxg1 expression in mouse medial pallium. J Neurosci. 2008 Oct 8;28(41):10415-21
1	J:170671 Shibata M, Nakao H, Kiyonari H, Abe T, Aizawa S, MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. J Neurosci. 2011 Mar 2;31(9):3407-22
1*	J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75
1*	J:90405 Shinozaki K, Yoshida M, Nakamura M, Aizawa S, Suda Y, Emx1 and Emx2 cooperate in initial phase of archipallium development. Mech Dev. 2004 May;121(5):475-89
1	J:248349 Smith R, Huang YT, Tian T, Vojtasova D, Mesalles-Naranjo O, Pollard SM, Pratt T, Price DJ, Fotaki V, The Transcription Factor Foxg1 Promotes Optic Fissure Closure in the Mouse by Suppressing Wnt8b in the Nasal Optic Stalk. J Neurosci. 2017 Aug 16;37(33):7975-7993
1*	J:154376 Stottmann RW, Tran PV, Turbe-Doan A, Beier DR, Ttc21b is required to restrict sonic hedgehog activity in the developing mouse forebrain. Dev Biol. 2009 Nov 1;335(1):166-78
1*	J:34768 Tremblay P, Pituello F, Gruss P, Inhibition of floor plate differentiation by Pax3: evidence from ectopic expression in transgenic mice. Development. 1996 Aug;122(8):2555-67
1*	J:96629 Vacalla CM, Theil T, Cst, a novel mouse gene related to Drosophila Castor, exhibits dynamic expression patterns during neurogenesis and heart development. Mech Dev. 2002 Oct;118(1-2):265-8
1	J:276573 Wiegering A, Petzsch P, Kohrer K, Ruther U, Gerhardt C, GLI3 repressor but not GLI3 activator is essential for mouse eye patterning and morphogenesis. Dev Biol. 2019 Jun 15;450(2):141-154
1	J:285763 Xu M, Han X, Liu R, Li Y, Qi C, Yang Z, Zhao C, Gao J, PDK1 Deficit Impairs the Development of the Dentate Gyrus in Mice. Cereb Cortex. 2019 Mar 1;29(3):1185-1198